Demystifying Medicine - TokeTheMost.com

What Effect Does Cannabis Use Have During Pregnancy?

March 3, 2022 Published by TokeTheMost

With the recent decriminalization and subsequent rise of Marijuana use around North America – researchers are finally beginning to discover some of the lesser known effects that Marijuana might have on human bodies. Many users of Marijuana are young people, and it has been estimated that approximately 50% of females who are Marijuana users continue their use during pregnancy (MGH Center for Women’s Mental Health, 2017).

This brings us to our question for today: What Effect Does Cannabis Use Have During Pregnancy?

Join us as we investigate this topic together!

Subscribe to the McMaster Demystifying Medicine YouTube channel: https://www.youtube.com/c/DemystifyingMedicine

This video is provided for general and educational information only. Please consult your health care provider for Information about your health.

This video was made by McMaster students Michelle Gavac, Navneet Narayanan, Kristyn Guglielmin, Kavian Taghizadeh, and Osama Hashmi in collaboration with the McMaster Demystifying Medicine Program

References:

Alvarez, Ana V. Gutierrez, et al. (2018). Neurodevelopmental outcomes and prenatal exposure to marijuana. Pediatrics, 142(1), pp.787. doi: 10.1542/peds.142.1_MeetingAbstract.787

Goldschmidt, L., Richardson, G., Willford, J., Severtson, S. and Day, N. (2012). School achievement in 14-year-old youths prenatally exposed to marijuana. Neurotoxicology and Teratology, 34(1), pp.161-167.

Goldschmidt, L., Richardson, G. A., Willford, J., & Day, N. L. (2008). Prenatal Marijuana Exposure and Intelligence Test Performance at Age 6. Journal of the American Academy of Child & Adolescent Psychiatry, 47(3), 254–263. doi: 10.1097/chi.0b013e318160b3f0

Keimpema, E., Mackie, K., & Harkany, T. (2011). Molecular model of cannabis sensitivity in developing neuronal circuits. Trends in Pharmacological Sciences, 32(9), 551–561. doi: 10.1016/j.tips.2011.05.004

Marroun, H. E., Tiemeier, H., Steegers, E. A., Jaddoe, V. W., Hofman, A., Verhulst, F. C., … Huizink, A. C. (2009). Intrauterine Cannabis Exposure Affects Fetal Growth Trajectories: The Generation R Study. Journal of the American Academy of Child & Adolescent Psychiatry, 48(12), 1173–1181. doi: 10.1097/chi.0b013e3181bfa8ee

MGH Center for Women’s Mental Health. (2017, March 29). The Effects of Marijuana on Embryo Development. Retrieved from https://womensmentalhealth.org/posts/effects-marijuana-embryo-development/?fbclid=IwAR2hSLchFxsvyR23mgwLln8Bmsjn3tDUhqVNkel3pN60BBs4oixcaRHEcAY

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Cannabis and Stress

September 13, 2021 Published by TokeTheMost

Cannabis is rapidly becoming one of the most consumed drugs in Canada. Many report using the drug as a coping mechanism for stress and anxiety. How exactly do our stress responses change in the presence of cannabis? Does cannabis actually relieve stress? This video considers the stress relieving effects of cannabis as it interacts with our body’s stress reaction system: the hypothalamic pituitary adrenal axis (HPA-axis). Followed by the potential of cannabis for treating chronic and acute stress related disorders. As research continues on the full uses of cannabis, this video serves as an overview of the research published thus far. If you are using cannabis to cope with stress, please do so safely by monitoring your usage, and reaching out to a registered healthcare professional for more guidance on coping with stress.

This video was made by McMaster students Armaan Sekhon, Kriti Manuja, Krishna Patel & Sharleen Maduranayagam in collaboration with the McMaster Demystifying Medicine Program.

References:

Canadian Centre on Substance Use and Addiction. (n.d.). Cannabis (Canadian Drug Summary) [Topic Summary]. Retrieved October 9, 2020, from https://www.ccsa.ca/cannabis-canadian-drug-summary
Childs, E., Lutz, J. A., & de Wit, H. (2017). Dose-related effects of delta-9-THC on emotional responses to acute psychosocial stress. Drug and Alcohol Dependence, 177, 136–144. https://doi.org/10.1016/j.drugalcdep.2017.03.030
Cuttler, C., Spradlin, A., Nusbaum, A. T., Whitney, P., Hinson, J. M., & McLaughlin, R. J. (2017). Blunted stress reactivity in chronic cannabis users. Psychopharmacology, 234(15), 2299–2309. https://doi.org/10.1007/s00213-017-4648-z
Gruber, S. A., Rogowska, J., & Yurgelun-Todd, D. A. (2009). Altered affective response in marijuana smokers: An FMRI study. Drug and Alcohol Dependence, 105(1–2), 139–153. https://doi.org/10.1016/j.drugalcdep.2009.06.019
Hyman, S. M., & Sinha, R. (2009). Stress-Related Factors in Cannabis Use and Misuse: Implications for Prevention and Treatment. Journal of Substance Abuse Treatment, 36(4), 400–413. https://doi.org/10.1016/j.jsat.2008.08.005
Micale, V., & Drago, F. (2018). Endocannabinoid system, stress and HPA axis. European Journal of Pharmacology, 834, 230–239. https://doi.org/10.1016/j.ejphar.2018.07.039
Orsolini, L., Chiappini, S., Volpe, U., De Berardis, D., Latini, R., Papanti, G. D., & Corkery, J. M. (2019). Use of Medicinal Cannabis and Synthetic Cannabinoids in Post-Traumatic Stress Disorder (PTSD): A Systematic Review. Medicina, 55(9). https://doi.org/10.3390/medicina55090525
Somaini, L., Manfredini, M., Amore, M., Zaimovic, A., Raggi, M. A., Leonardi, C., Gerra, M. L., Donnini, C., & Gerra, G. (2012). Psychobiological responses to unpleasant emotions in cannabis users. European Archives of Psychiatry and Clinical Neuroscience, 262(1), 47–57. https://doi.org/10.1007/s00406-011-0223-5
Turna, J., Patterson, B., & Van Ameringen, M. (2017). Is cannabis treatment for anxiety, mood, and related disorders ready for prime time? Depression and Anxiety, 34(11), 1006–1017. https://doi.org/10.1002/da.22664

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Marijuana use during pregnancy: Is it safe?

July 19, 2021 Published by TokeTheMost

In this video we dive into the facts and myths about marijuana use during pregnancy. Research to date does not support the use of marijuana during pregnancy, despite its effectiveness in providing relief for pregnancy symptoms.

Subscribe to the McMaster Demystifying Medicine YouTube channel: https://www.youtube.com/c/DemystifyingMedicine

This video is provided for general and educational information only. Please consult your health care provider for Information about your health.

This video was made by McMaster students Priyanka Lamba, Makenzie Lamb, and Purviben Mahida in collaboration with the McMaster Demystifying Medicine Program

#DemystifyingMedicine

References:

Briscoe, J., & Casarett, D. (2018). Medical Marijuana Use in Older Adults. Journal of the
American Geriatrics Society, 66(5), 859-863. doi:10.1111/jgs.15346

CDC. (2018, March 16). What You Need to Know About Marijuana Use and Pregnancy. Retrieved November 27, 2020, from https://www.cdc.gov/marijuana/factsheets/pregnancy.htm

Commissioner, O. (n.d.). What You Should Know About Using CBD When Pregnant or Breastfeeding. Retrieved November 28, 2020, from https://www.fda.gov/consumers/consumer-updates/what-you-should-know-about-using-cannabis-including-cbd-when-pregnant-or-breastfeeding

Gunn, J. K., Rosales, C. B., Center, K. E., Nuñez, A., Gibson, S. J., Christ, C., & Ehiri, J. E. (2016). Prenatal exposure to cannabis and maternal and child health outcomes: A systematic review and meta-analysis. BMJ Open, 6(4). doi:10.1136/bmjopen-2015-009986

Hildreth, D. (n.d.). What Are Topicals? Retrieved November 21, 2020, from https://ocs.ca/blogs/facts-about-cannabis-consumption/what-are-topicals

Hildreth, D. (n.d.). Topical Potency. Retrieved November 21, 2020, from https://ocs.ca/blogs/facts-about-cannabis-consumption/topicals-potency

Katrina, M., Gryczynski, J., Axenfeld, E., Schwartz, R.P., Terplan, M. (2017). “Pregnant Womenʼs Current and Intended Cannabis Use in Relation to Their Views Toward Legalization and Knowledge of Potential Harm.” Journal of Addiction Medicine 11(3):211–16. doi: 10.1097/ADM.0000000000000299.

National Institute on Drug Abuse. (2019, December). Marijuana DrugFacts. Retrieved from
https://www.drugabuse.gov/publications/drugfacts/marijuana

Parmar, J. R., Forrest, B. D., & Freeman, R. A. (2016). Medical marijuana patient counseling
points for health care professionals based on trends in the medical uses, efficacy, and adverse effects of cannabis-based pharmaceutical drugs. Research in Social and Administrative Pharmacy, 12(4), 638-654. doi:https://doi.org/10.1016/j.sapharm.2015.09.002

Premium Jane. (2019, September 27). Hemp vs. Marijuana: What Is the Difference? Retrieved
from https://premiumjane.com/blog/difference-between-cannabis-and-hemp/

Public Health Ontario. (2018). Brief effects of cannabis exposure during pregnancy and breastfeeding. Retrieved from https://www.publichealthontario.ca/-/media/documents/E/2018/eb-cannabis-pregnancy-breastfeeding.pdf?la=en

Sarrafpour, S., Urits, I., Powell, J. et al. (2020). Considerations and Implications of Cannabidiol Use During Pregnancy. Curr Pain Headache Rep 24, 38 https://doi.org/10.1007/s11916-020-00872-w

Singh, M. (2019, July 23). Medical VS Recreational Cannabis: Blog: Apollo. Retrieved from
https://apollocannabis.ca/medical-vs-recreational-cannabis-in-canada/

Zumbrun, E.E., Sido, J.M., Nagarkatti, P.S. et al. (2020). Epigenetic Regulation of Immunological Alterations Following Prenatal Exposure to Marijuana Cannabinoids and its Long Term Consequences in Offspring. J Neuroimmune Pharmacol 10, 245–254 https://doi.org/10.1007/s11481-015-9586-0

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CBD and Anxiety

January 25, 2021 Published by TokeTheMost

Are you feeling anxious from schoolwork? Using hemp-derived CBD may help. We explain the difference between CBD derived from hemp versus marijuana, how effective the hemp-derived variant treats anxiety, and how you can incorporate CBD into your wellness routine.

Disclaimer! This video does not substitute medical advice, and further research should be done before the participation in any CBD or THC products. Please consult your health professional to learn and understand what may work best for you. If you want to learn more in depth about what long-term research is currently being done surrounding recreational CBD use, the science behind how CBD can be effective, or it’s efficacy; please follow the links below.

This video was made by McMaster students; Vanessa D’Ambrosio, Jia Hui Du, and Jennifer Dang in collaboration with the McMaster Demystifying Medicine Program.

#DemystifyingMedicine, #MentalHealth

o Cannabidiol (CBD) — what we know and what we don’t (Harvard University Health): https://www.health.harvard.edu/blog/cannabidiol-cbd-what-we-know-and-what-we-dont-2018082414476
o Dosage, Efficacy and Safety of Cannabidiol Administration in Adults: A Systematic Review of Human Trials (Journal of Clinical Medicine Research): https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7092763/
o What Research Says about CBD oil (Northwestern Medicine): https://www.nm.org/healthbeat/medical-advances/science-and-research/what-research-says-about-cbd-oil
o Using CBD Oil for Anxiety: Does It Work? (HealthLine): https://www.healthline.com/health/cbd-for-anxiety#what-research-says
o Cannabidiol as a Potential Treatment for Anxiety Disorders (Journal of Neurotherapeutics) : https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4604171/
o Effects of Hemp Extract on Markers of Wellness, Stress Resilience, Recovery and Clinical Biomarkers of Safety in Overweight, But Otherwise Healthy Subjects (Journal of Dietary Supplements) RESEARCH REFERRED TO IN VIDEO: https://www.tandfonline.com/doi/pdf/10.1080/19390211.2020.1765941?casa_token=pq5tlLJ6HrAAAAAA:pAqNEe88AH_Tyx6WlGZ5EzoWxfkfsC8Wc7n80hY7ccb4WDQ7gVWhlkAiHlUC2UWeuVIE

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Tag: Demystifying Medicine